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Knip Tablets

Knip Tablet is a combination of Nimesulide, a selective COX-2 inhibitor with anti-inflammatory and analgesic effects, and Paracetamol, a widely trusted antipyretic and pain reliever. Together, they offer fast and effective relief from fever, inflammation, and mild to moderate pain of various origins. Knip is ideal for short-term use in acute pain conditions.

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Uses / Indications:
  • Fever (with or without body pain)

  • Muscular and joint pain

  • Headache and migraine

  • Dental pain

  • Backache and post-traumatic pain

  • Menstrual cramps

  • Pain due to sprains or strains

Dosage & Administration:
  • Adults: 1 tablet twice daily after meals, or as prescribed by a physician

  • Route: Oral

  • Note: Not recommended for children under 12 years unless directed by a physician

  • Do not use for more than 10 days continuously

Mechanism of Action:
  • Nimesulide selectively inhibits the enzyme COX-2, which reduces the synthesis of prostaglandins responsible for pain and inflammation.

  • Paracetamol works by inhibiting prostaglandin synthesis in the central nervous system, reducing pain and fever.

Side Effects:

Common:

  • Nausea

  • Heartburn

  • Dizziness

  • Stomach discomfort

Rare but Serious:

  • Liver toxicity (especially with long-term use)

  • Skin rash or hypersensitivity reactions

  • Gastritis or gastrointestinal bleeding

  • Kidney impairment (with prolonged use)

Precautions:
  • Not recommended for children, pregnant or lactating women

  • Avoid in patients with liver dysfunction, renal impairment, or gastric ulcers

  • Avoid alcohol and other hepatotoxic drugs

  • Use only under medical supervision for short-term treatment

Storage:

Store in a cool and dry place below 25°C. Protect from light and moisture. Keep out of reach of children.

Disclaimer:

Knip Tablet should be taken only on a doctor’s prescription. Prolonged or unsupervised use can pose health risks, especially related to the liver.